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Immune responses in the nervous system

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Published by Bios Scientific Publishers in Oxford, UK .
Written in English


  • Nervous system -- Immunology.,
  • Neuroimmunology.

Book details:

Edition Notes

Includes bibliographical references and index.

Statement[edited by] Nancy J. Rothwell.
SeriesThe Molecular and cellular neurobiology series
ContributionsRothwell, Nancy.
LC ClassificationsQP356.47 .I45 1995
The Physical Object
Paginationxvi, 233 p. :
Number of Pages233
ID Numbers
Open LibraryOL430213M
ISBN 101872748791
LC Control Number98137466

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Get this from a library! Immune responses in the nervous system. [Nancy Rothwell;] -- This text brings together an internationally recognised group of authorities who address a range of topical issues relating to this important and growing field. Immediate (Type I) Hypersensitivity. Antigens that cause allergic responses are often referred to as allergens. The specificity of the immediate hypersensitivity response is predicated on the binding of allergen-specific IgE to the mast cell surface. The process of producing allergen-specific IgE is called sensitization, and is a necessary prerequisite for the symptoms of immediate. The immune system is a host defense system comprising many biological structures and processes within an organism that protects against function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy many species, there are two major subsystems of the immune. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects.

Immune responses occurring within the central nervous system (CNS) have unique features attributable to the cellular and functional organization of the CNS and to the presence of the blood-brain. The immune system can be divided into two overlapping mechanisms to destroy pathogens: the innate immune response, which is relatively rapid but nonspecific and thus not always effective, and the adaptive immune response, which is slower in its development during an initial infection with a pathogen, but is highly specific and effective at attacking a wide variety of pathogens (). This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes. This book covers developmental aspects of immune/inflammatory responses in the CNS and basic aspects of glial . Immune responses in some mucosal tissues such as the Peyer’s patches (see Figure ) in the small intestine take up particulate antigens by specialized cells known as microfold or M cells (Figure ). These cells allow the body to sample potential pathogens from the intestinal lumen.

Major contributors to the innate immune system include epithelial cells, which prevent pathogen entry, phagocytes such as neutrophils and macrophages, the complement system, and pattern recognition receptors. In contrast to the innate immune system, the adaptive immune system provides highly specific responses to the invading by: 6. Immune and Inflammatory Responses in the Nervous System covers developmental aspects of immune/inflammatory responses in the CNS, basic aspects of glial function, as well as inflammatory mediators, their mechanisms of action, clinical importance and sites of : Nancy Rothwell. Abstract. The central nervous system (CNS) is relatively isolated from systemic immune responses in the absence of disease. Within the normal CNS, there is no mechanism for antibody production, no lymphatic system, and few if any phagocytic by: 6.   The tenet of the immune system is the protection of the host against both invading pathogens and autoimmune diseases that arise in genetically susceptible individuals. For the former, it is essential to mount robust immune responses, both T-cell-mediated immunity and antibody production, against a myriad of : Sundararajan Jayaraman, Bellur S. Prabhakar.